| | | | | | | | | | | | | | |
| Subsidiary | | Jurisdiction of Incorporation or Organization | | Ownership by Endo International plc |
| 70 Maple Avenue, LLC | | Delaware | | Indirect |
| Actient Pharmaceuticals LLC | | Delaware | | Indirect |
| Actient Therapeutics, LLC | | Delaware | | Indirect |
| Anchen Incorporated | | New York | | Indirect |
| Anchen Pharmaceuticals, Inc. | | Delaware | | Indirect |
| Astora Women's Health Bermuda ULC | | Bermuda | | Indirect |
| Astora Women's Health Ireland Limited | | Ireland | | Indirect |
| Astora Women's Health Technologies | | Ireland | | Indirect |
| Astora Women's Health, LLC | | Delaware | | Indirect |
| Auxilium International Holdings, LLC | | Delaware | | Indirect |
| Auxilium Pharmaceuticals, LLC | | Delaware | | Indirect |
| Auxilium US Holdings, LLC | | Delaware | | Indirect |
| Bermuda Acquisition Management Limited | | Bermuda | | Indirect |
| BioSpecifics Technologies LLC | | Delaware | | Indirect |
| Branded Operations Holdings, Inc. | | Delaware | | Indirect |
| CPEC LLC | | Delaware | | Indirect |
| DAVA International, LLC | | Delaware | | Indirect |
| DAVA Pharmaceuticals, LLC | | Delaware | | Indirect |
| Endo Aesthetics LLC | | Delaware | | Indirect |
| Endo Bermuda Finance Limited | | Bermuda | | Indirect |
| Endo Designated Activity Company | | Ireland | | Direct |
| Endo Eurofin Unlimited Company | | Ireland | | Indirect |
| Endo Finance IV Unlimited Company | | Ireland | | Indirect |
| Endo Finance LLC | | Delaware | | Indirect |
| Endo Finance Operations LLC | | Delaware | | Indirect |
| Endo Finco Inc. | | Delaware | | Indirect |
| Endo Generics Holdings, Inc. | | Delaware | | Indirect |
| Endo Global Aesthetics Limited | | Ireland | | Indirect |
| Endo Global Biologics Unlimited Company | | Ireland | | Indirect |
| Endo Global Development Limited | | Ireland | | Indirect |
| Endo Global Finance LLC | | Delaware | | Indirect |
| Endo Global Ventures | | Bermuda | | Indirect |
| Endo Health Solutions Inc. | | Delaware | | Indirect |
| Endo India Holdings, LLC | | Delaware | | Indirect |
| Endo Innovation Valera, LLC | | New York | | Indirect |
| Endo Ireland Finance II Limited | | Ireland | | Indirect |
| Endo LLC | | Delaware | | Indirect |
| Endo Luxembourg Finance Company I S.a r.l. | | Luxembourg | | Indirect |
| Endo Luxembourg Holding Company S.a r.l. | | Luxembourg | | Indirect |
| Endo Luxembourg International Financing S.a r.l. | | Luxembourg | | Indirect |
| Endo Management Limited | | Ireland | | Indirect |
| Endo Par Innovation Company, LLC | | Delaware | | Indirect |
| Endo Pharmaceuticals Finance LLC | | Delaware | | Indirect |
| Endo Pharmaceuticals Inc. | | Delaware | | Indirect |
| Endo Pharmaceuticals Solutions Inc. | | Delaware | | Indirect |
| Endo Pharmaceuticals Valera Inc. | | Delaware | | Indirect |
| Endo Procurement Operations Limited | | Ireland | | Indirect |
| Endo TopFin Limited | | Ireland | | Indirect |
| Endo U.S. Inc. | | Delaware | | Indirect |
| Endo US Holdings Luxembourg I S.a r.l. | | Luxembourg | | Indirect |
| Endo Ventures Aesthetics Limited | | Ireland | | Indirect |
| Endo Ventures Bermuda Limited | | Bermuda | | Indirect |